一、基本情况

姓名：丁飞

性别：男

籍贯：江苏省南京市

出生年月：1982年6月

职称：教授

学位：博士

硕/博导：硕士研究生导师

二、 学习工作经历

2014年9月－至今，青岛农业大学，植物医学学院，教授

2014年2月－2014年8月，中国农业大学，资源与环境学院，博士后

2011年2月－2013年1月，麻省理工学院，生物工程系，合作研究

2007年9月－2014年1月，中国农业大学，理学院，硕博连读

2006年7月－2007年8月，中国矿业大学，化工学院，助理研究员

2002年9月－2006年6月，中国矿业大学，化工学院，本科

三、 教学工作

本科生必修课《植物化学保护学》、《植物化学保护学实验》，选修课《农药残留分析与检测技术》、《农药残留分析与检测技术实验》

• 研究方向及简介

1. 农药/药物分子设计

2. 农药分子毒理学

五、 科研课题

1. 新农药创制与开发国家重点实验室开放基金（No.: 2016NYRD02），项目起止时间：2017年3月－2018年2月

2. 山东省自然科学基金（No.: ZR2016CQ02），项目起止时间：2016年11月－2019年6月

3. 山东省自然科学基金（No.: ZR2016CP19），项目起止时间：2016年11月－2019年6月

4. 山东省高等学校科技计划项目（No.: J16LF05），项目起止时间：2016年1月－2018年12月

5. 青岛农业大学高层次人才科研基金（No.: 1116011），项目起止时间：2016年5月－2018年4月

6. 国家自然科学基金（No.: 31171693），项目起止时间：2012年1月－2015年12月

六、主要成果

论文情况：

以第一作者/通讯作者身份，在美国化学会（ACS Publications）、英国皇家化学会（RSC Publishing）、Elsevier B.V.、Springer、Wiley等数据库SCI源期刊发表研究论文40余篇，论文总“他引”次数：700余次（部分论文已进入ESI“高被引论文”前1%），其中，二篇论文分别被英国皇家化学会期刊《Molecular BioSystems》和《Physical Chemistry Chemical Physics》选为封面文章，一篇论文入选期刊《Molecular BioSystems》的Themed Collection，18篇论文发表在美国权威Thomson Reuters 2016 Journal Citation Reports一区期刊。近三年代表性论文：

1. Peng, W.; Ding, F.*; Peng, Y.-K.; Xie, Y. Biological effects of α-adrenergic phentolamine on erythrocyte hemeprotein: Molecular insights from biorecognition behavior, protein dynamics and flexibility. J. Photochem. Photobiol. B: Biol. 2017, 171, 75-84. (*通讯作者)

2. Ding, F.; Peng, W.; Peng, Y.-K. Biophysical exploration of protein-flavonol recognition: Effects of molecular properties and conformational flexibility. Phys. Chem. Chem. Phys. 2016, 18, 11959-11971. (封面文章)

3. Ding, F.; Xie, Y.; Peng, W.; Peng, Y.-K. Measuring the bioactivity and molecular conformation of typically globular proteins with phenothiazine-derived methylene blue in solid and in solution: A comparative study using photochemistry and computational chemistry. J. Photochem. Photobiol. B: Biol. 2016, 158, 69-80.

4. Ding, F.; Peng, W. Biophysical evaluation of protein structural flexibility for ligand biorecognition in solid solution. Phys. Chem. Chem. Phys. 2016, 18, 6595-6606.

5. Peng, W.; Ding, F.*; Peng, Y.-K. In vitro evaluation of the conjugations of neonicotinoids with transport protein: Photochemistry, ligand docking and molecular dynamics studies. RSC Adv. 2016, 6, 1826-1843. (*通讯作者)

6. Peng, W.; Ding, F.*; Xie, Y. Biointeractions of C.I. Acid Red 2 and its structural analogues with transporter albumin: Fluorescence, circular dichroism, and ligand docking approaches. J. Photochem. Photobiol. B: Biol. 2016, 154, 40-50. (*通讯作者)

7. Peng, W.; Ding, F.* Biomolecular recognition of antagonists by α7 nicotinic acetylcholine receptor: Antagonistic mechanism and structure-activity relationships studies. Eur. J. Pharm. Sci. 2015, 76, 119-132. (*通讯作者)

8. Ding, F.; Peng, W.; Chao, M.-W.; Peng, Y.-K. Realizing the recognition features of model antipsychotic compounds by important protein: Photochemical and computational studies. J. Photochem. Photobiol. B: Biol. 2015, 148, 21-30.

9. Ding, F.; Peng, W. Biological assessment of neonicotinoids imidacloprid and its major metabolites for potentially human health using globular proteins as a model. J. Photochem. Photobiol. B: Biol. 2015, 147, 24-36.

10. Ding, F.; Peng, W. Biological activity of natural flavonoids as impacted by protein flexibility: An example of flavanones. Mol. BioSyst. 2015, 11, 1119-1133. (Themed Collection: Chemical Biology in Molecular BioSystems)

11. Ding, F.; Peng, W.; Peng, Y.-K.; Jiang, Y.-T. Renal protein reactivity and stability of antibiotic amphenicols: Structure and affinity. Mol. BioSyst. 2014, 10, 2509-2516. (封面文章)

12. Peng, W.; Ding, F.*; Jiang, Y.-T.; Peng, Y.-K. Bioavailability and activity of natural food additive triterpenoids as influenced by protein. J. Agric. Food Chem. 2014, 62, 2271-2283. (*通讯作者)

获奖情况：

1. 中国农业大学“校级优秀博士学位论文”，中国农业大学，2014年

2. 北京市“优秀毕业生”，北京市教育委员会，2014年

3. 中国农业大学“优秀研究生毕业生”，中国农业大学，2014年

七、 社会兼职

1. 美国化学会（American Chemical Society）会员、英国皇家化学会（Royal Society of Chemistry）会员、日本光化学协会会员（Japanese Photochemistry Association）

2. 加拿大食品科学与技术协会（Canadian Institute of Food Science and Technology）官方刊物、SCI源期刊《Food Research International》编辑、编委会成员（Editorial Board）

3. Bentham Science Publishers数据库SCI源期刊《Combinatorial Chemistry & High Throughput Screening》、《Current Drug Metabolism》、《Current Medicinal Chemistry》、《Current Topics in Medicinal Chemistry》客座编辑（Guest Editor）

4. 兼任40多个欧/美SCI源期刊审稿人，例如美国化学会期刊Biomacromolecules、J. Agric. Food Chem.、J. Phys. Chem. B、Mol. Pharmaceutics，英国皇家化学会期刊Anal. Methods、Mol. BioSyst.、Phys. Chem. Chem. Phys.、RSC Adv.等

八、联系方式

通讯地址：山东省青岛市城阳区长城路700号，青岛农业大学植物医学学院

邮政编码：266109

联系电话：0532-86080028

E-mail: feiding@cau.edu.cn

1.Basic Situation

Name: Ding Fei

Sex: Male

Native place: Nanjing, Jiangsu Province

Date of birth: June 1982

Title: Professor

Degree: Doctor

Master / Ph.D.: Master Instructor

2.Learning Work Experience

In September 2014 - so far，Qingdao Agricultural University，College of Plant Medicine，Professor

In February 2014－In August 2014，China Agricultural University，College Of Resource And Environment, Postdoctoral

In February 2011－In January 2013，Massachusetts Institute of Technology，Department of Biological Engineering, Cooperation

In September 2007－In January 2014，China Agricultural University，College of Science，Master blog read

In July 2006－In August 2007，China University of Mining and Technology, College of Chemical Engineering, Assistant Researcher

In September 2002－In June 2006，China University of Mining and Technology, College of Chemical Engineering, Undergraduate

3.Teaching Work

Undergraduate students compulsory course "phytochemical protection", "plant chemical protection experiment", elective course "pesticide residue analysis and detection technology", "pesticide residue analysis and detection technology experiment"

4.Research Direction And Profile

1. )Pesticide / Drug Molecular Design

2. )Molecular toxicology of pesticides

5.Research Subject

1. )State Key Laboratory of New Pesticide Creation and Development（No.: 2016NYRD02），Project start and end time：In May 2017

－In February 2018

2. )Natural Science Foundation of Shandong Province（No.: ZR2016CQ02），Project start and end time：In November 2016－In June 2019

3. )Natural Science Foundation of Shandong Province（No.: ZR2016CP19），Project start and end time：In November 2016－In June 2019

4.) Shandong Province Science and Technology Project of Higher Education（No.: J16LF05），Project start and end time：In January 2016－In December 2018

5. )Qingdao Agricultural University high - level talent research fund（No.: 1116011），Project start and end time：In May 2016－In April 2018

6.) National Natural Science Foundation of China（No.: 31171693），Project start and end time：In January 2012－In December 2015

6.Main Result

Thesis situation:

以第一作者/通讯作者身份，在美国化学会（ACS Publications）、英国皇家化学会（RSC Publishing）、Elsevier B.V.、Springer、Wiley等数据库SCI源期刊发表研究论文40余篇，论文总“他引”次数：700余次（部分论文已进入ESI“高被引论文”前1%），其中，二篇论文分别被英国皇家化学会期刊《Molecular BioSystems》和《Physical Chemistry Chemical Physics》选为封面文章，一篇论文入选期刊《Molecular BioSystems》的Themed Collection，18篇论文发表在美国权威Thomson Reuters 2016 Journal Citation Reports一区期刊。近三年代表性论文：

1. Peng, W.; Ding, F.*; Peng, Y.-K.; Xie, Y. Biological effects of α-adrenergic phentolamine on erythrocyte hemeprotein: Molecular insights from biorecognition behavior, protein dynamics and flexibility. J. Photochem. Photobiol. B: Biol. 2017, 171, 75-84. (*通讯作者)

2. Ding, F.; Peng, W.; Peng, Y.-K. Biophysical exploration of protein-flavonol recognition: Effects of molecular properties and conformational flexibility. Phys. Chem. Chem. Phys. 2016, 18, 11959-11971. (封面文章)

3. Ding, F.; Xie, Y.; Peng, W.; Peng, Y.-K. Measuring the bioactivity and molecular conformation of typically globular proteins with phenothiazine-derived methylene blue in solid and in solution: A comparative study using photochemistry and computational chemistry. J. Photochem. Photobiol. B: Biol. 2016, 158, 69-80.

4. Ding, F.; Peng, W. Biophysical evaluation of protein structural flexibility for ligand biorecognition in solid solution. Phys. Chem. Chem. Phys. 2016, 18, 6595-6606.

5. Peng, W.; Ding, F.*; Peng, Y.-K. In vitro evaluation of the conjugations of neonicotinoids with transport protein: Photochemistry, ligand docking and molecular dynamics studies. RSC Adv. 2016, 6, 1826-1843. (*通讯作者)

6. Peng, W.; Ding, F.*; Xie, Y. Biointeractions of C.I. Acid Red 2 and its structural analogues with transporter albumin: Fluorescence, circular dichroism, and ligand docking approaches. J. Photochem. Photobiol. B: Biol. 2016, 154, 40-50. (*通讯作者)

7. Peng, W.; Ding, F.* Biomolecular recognition of antagonists by α7 nicotinic acetylcholine receptor: Antagonistic mechanism and structure-activity relationships studies. Eur. J. Pharm. Sci. 2015, 76, 119-132. (*通讯作者)

8. Ding, F.; Peng, W.; Chao, M.-W.; Peng, Y.-K. Realizing the recognition features of model antipsychotic compounds by important protein: Photochemical and computational studies. J. Photochem. Photobiol. B: Biol. 2015, 148, 21-30.

9. Ding, F.; Peng, W. Biological assessment of neonicotinoids imidacloprid and its major metabolites for potentially human health using globular proteins as a model. J. Photochem. Photobiol. B: Biol. 2015, 147, 24-36.

10. Ding, F.; Peng, W. Biological activity of natural flavonoids as impacted by protein flexibility: An example of flavanones. Mol. BioSyst. 2015, 11, 1119-1133. (Themed Collection: Chemical Biology in Molecular BioSystems)

11. Ding, F.; Peng, W.; Peng, Y.-K.; Jiang, Y.-T. Renal protein reactivity and stability of antibiotic amphenicols: Structure and affinity. Mol. BioSyst. 2014, 10, 2509-2516. (封面文章)

12. Peng, W.; Ding, F.*; Jiang, Y.-T.; Peng, Y.-K. Bioavailability and activity of natural food additive triterpenoids as influenced by protein. J. Agric. Food Chem. 2014, 62, 2271-2283. (*通讯作者)

Awards:

1.) China Agricultural University "excellent doctoral degree thesis", China Agricultural University, 2014

2.) Beijing "outstanding graduates", Beijing Municipal Education Commission, 2014

3.) China Agricultural University "outstanding graduate students", China Agricultural University, 2014

7.Social Part-Time

1. 美国化学会（American Chemical Society）会员、英国皇家化学会（Royal Society of Chemistry）会员、日本光化学协会会员（Japanese Photochemistry Association）

2. 加拿大食品科学与技术协会（Canadian Institute of Food Science and Technology）官方刊物、SCI源期刊《Food Research International》编辑、编委会成员（Editorial Board）

3. Bentham Science Publishers数据库SCI源期刊《Combinatorial Chemistry & High Throughput Screening》、《Current Drug Metabolism》、《Current Medicinal Chemistry》、《Current Topics in Medicinal Chemistry》客座编辑（Guest Editor）

4. 兼任40多个欧/美SCI源期刊审稿人，例如美国化学会期刊Biomacromolecules、J. Agric. Food Chem.、J. Phys. Chem. B、Mol. Pharmaceutics，英国皇家化学会期刊Anal. Methods、Mol. BioSyst.、Phys. Chem. Chem. Phys.、RSC Adv.等

8. contact information

Address: No. 700, Changcheng Road, Chengyang District, Qingdao City, Shandong Province, Qingdao Agricultural University, College of Plant Medicine

Post code: 266109

Tel: 0532-86080028

E-mail:feiding@cau.edu.cn