李敬涛

时间:2020-03-10 16:18:08

一、基本情况

李敬涛,男,1987年出生,博士,副教授,硕士生导师。主要研究番茄枯萎病、灰霉病致病机制及防治研究。主持国家自然科学基金,山东省自然科学基金等多个科研项目。发表论文27余篇,其中SCI论文21篇;授权国家发明专利6项。

二、 学习工作经历

工作经历:

2019.02---至今:青岛农业大学植物医学学院 副教授

2018.08---2019.02:青岛农业大学植物医学学院 讲师

2017.12----2018.07 吉林大学 科研助理

学习经历:

2015.08----2017.08 佛罗里达大学 博士(联合培养)

2013.07----2017.12 吉林大学 博士

2011.09----2013.07 吉林大学 硕士

2007.09----2011.07 青岛农业大学 本科

三、 教学工作

主讲《普通植物病理学》、《科技论文写作》等课程。

四、 研究方向及简介

研究方向为分子植物病理学,主要以番茄枯萎病原尖孢镰刀菌为研究材料,通过蛋白质组学方法鉴定与病原菌致病性密切相关的修饰(乙酰化)蛋白,在此基础上综合应用植物病理学、分子遗传学、生物化学等多种手段研究蛋白功能及作用机制,解析乙酰化修饰的生物学意义,最终阐明植物-病原菌相互作用新机制,为通过设计药物或者转基因手段控制植物病害的发生以及最终提高作物产量奠定分子基础。

五、 科研课题

1. 尖孢镰刀菌效应蛋白FolSVP2乙酰化修饰调控其致病力的分子机制(32272489),2022年国家自然科学基金面上基金,主持。

2. 尖孢镰刀菌番茄专化型乙酰化分泌蛋白FolSVP1功能解析(31901830),2019年国家自然科学基金青年基金,主持。

3. 尖孢镰刀菌效应蛋白FolSVP1的功能及作用机制研究(ZR201808100017), 2019年山东省自然科学基金博士基金,主持。

4. 烟草青枯菌无毒基因鉴定及寄主抗病机制研究。2022年,中国农业科学院烟草研究所。横向课题,主持。

5. 尖孢镰刀菌FolSVP1蛋白致病机制研究,高层次人才启动基金项目,主持。

六、主要成果

l 论文

  1. Jingtao Li, Chenyang Wang, Limei Yang, Fahui Qiu, Yue Li, Yaning Zheng, Sihui Liu, Limin Song, and Wenxing Liang. Enhancing tomato resistance by exploring early defense events against Fusarium wilt disease. Phytopathology Research. 2023; 5: 24.
  2. Chenyang Wang, Yaning Zheng, Zhishan Liu, Yongpan Qian, Yue Li, Limei Yang, Sihui Liu, Wenxing Liang, and Jingtao Li (2023). The secreted FolAsp aspartic protease facilitates virulence of Fusarium oxysporum f. sp. lycopersici. Front. Microbiol. 14:1103418.
  3. Jingtao Li, Xiaoying Ma, Chenyang Wang, Sihui Liu, Gang Yu, Mingming Gao,Hengwei Qian, Mengjie Liu, Ben F. Luisi, Dean W. Gabriel, Wenxing Liang.(2022) Acetylation of a fungal effector that translocates host PR1 facilitates virulence. eLife, 11: p. e82628.
  4. Jingtao Li(#), Chenyang Wang(#), Wenxing Liang, and Sihui Liu (2021). Rhizosphere Microbiome: The Emerging Barrier in Plant-Pathogen Interactions. Front. Microbiol. 12.
  5. Jingtao Li(#), Mingming Gao(#), Dean W Gabriel, Wenxing Liang, Limin Song. (2020) Secretome-Wide Analysis of Lysine Acetylation in Fusarium oxysporum f. sp. lycopersici Provides Novel Insights Into Infection-Related Proteins Front Microbiol. 2020 Sep 8;11:559440.
  6. Genglin Zhu, Gang Yu(#), Xianghui Zhang, Jinliang Liu, Yanhua Zhang, Jeffrey A. Rollins, Jingtao Li(#), Hongyu Pan(#). (2019) The formaldehyde dehydrogenase SsFdh1 is regulated by and functionally cooperates with the GATA transcription factor SsNsd1 in Sclerotinia sclerotiorum. mSystems, 4, e00397-00319.
  7. Tingtao Xu(#), Jingtao Li(#), Baodong Yu(#), Ling Liu, Xianghui Zhang, Jinliang Liu, Hongyu Pan and Yanhua Zhang. (2018) Transcription factor SsSte12 was involved in mycelium growth and development in Sclerotinia sclerotiorum. Frontiers in Microbiology, 9, doi: 10.3389/fmicb.2018.02476.
  8. Jingtao Li(#), Xianghui Zhang(#), Le Li., Jinliang Liu., Yanhua Zhang and Hongyu Pan. Proteomics analysis of SsNsd1-mediated compound appressoria formation in Sclerotinia sclerotiorum. Int J Mol Sci, (2018) 19, 2946.
  9. Jingtao Li, Yanhua Zhang, Yucheng Zhang, Pei-Ling Yu, Hongyu Pan, Jeffrey A. Rollins. Introduction of large sequence inserts by CRISPR-Cas9 creates pathogenicity mutants in the multinucleate filamentous pathogen Sclerotinia sclerotiorum. mBio (2018) 9, e00567-00518
  10. Jingtao Li, Wenhui Mu, Selvakumar Veluchamy, Yanzhi Liu, Yanhua Zhang, Hongyu Pan and Jeffrey A. Rollins. The GATA-type IVb zinc-finger transcription factor SsNsd1 regulates asexual-sexual development and appressoria formation in Sclerotinia sclerotiorum. Mol Plant Pathol. (2018) 19, 1679-1689.
  11. Jingtao Li, Gang Yu, Xinhua Sun, Xianghui Zhang, Jinliang Liu, Hongyu Pan. AcEBP1, an ErbB3-Binding Protein (EBP1) from halophyte Atriplex canescens, negatively regulates cell growth and stress responses in Arabidopsis. Plant science (2016) 248:64-74
  12. Jingtao Li(#), Gang Yu(#), Xinhua Sun, Yanzhi Liu, Jinliang Liu, Xianghui Zhang, Chengguo Jia, Hongyu Pan. AcPIP2, a plasma membrane intrinsic protein from halophyte Atriplex canescens, enhances plant growth rate and abiotic stress tolerance when overexpressed in Arabidopsis thaliana. Plant Cell Rep (2015) 34:1401–1415
  13. Jingtao Li, Xinhua Sun, Gang Yu, Chengguo Jia, Jinliang Liu and Hongyu Pan. Generation and Analysis of Expressed Sequence Tags (ESTs) from Halophyte Atriplex canescens to Explore Salt-Responsive Related Genes. Int. J. Mol. Sci. (2014) 15, 11172-11189. IF:2.862
  14. J.T. Li(#), G. Yu(#), X.H. Sun, C.G. Jia, Q. Du, Q.Y. Li and H.Y. Pan. Modification of vectors for functional genomics analysis in plants. Genet. Mol. Res. (2014) 13 (3): 7815-7825.
  15. Xinhua Sun, Gang Yu, Jingtao Li, Jinliang Liu, Xueliang Wang, Genglin Zhu, Xianghui Zhang, Hongyu Pan. AcERF2, an ethylene-responsive factor of Atriplex canesce ns, positively modulates osmotic and disease resistance in Arabidopsis thaliana. Plant Science (2018), 274, 32-43. Plant science
  16. Gang Yu, Jingtao Li, Xinhua Sun, Yanzhi Liu, Xueliang Wang, Hao Zhang, Hongyu Pan. Exploration for the salinity tolerance related genes from xero-halophyte Atriplex canescens exploiting yeast functional screening system. Int. J. Mol. Sci. (2017) 18(11), 2444
  17. Gang Yu, Jingtao Li, Xinhua Sun, Xianghui Zhang, Jinliang Liu, Hongyu Pan. Overexpression of AcNIP5;1, a Novel Nodulin-Like Intrinsic Protein from Halophyte Atriplex canescens, Enhances Sensitivity to Salinity and Improves Drought Tolerance in Arabidopsis. Plant Mol Biol Rep. (2015) 33:1864–1875
  18. Gang Yu, Liqin Xie, Jingtao Li, Xinhua Sun, Hao Zhang, Qian Du, Qiyun Li, Shihong Zhang, Hongyu Pan. Isolation, partial characterization, and cloning of an extracellular chitinase from the entomopathogenic fungus Verticillium lecanii. Genet. Mol. Res. (2015) 14 (1): 2275-2289
  19. Ye Tao, Fengting Wang, Dongmei Jia, Jingtao Li, Ya me i Zhang, Chengguo Jia, Dongping Wang, Hongyu Pan. Cloning and Functional Analysis of the Promoter of a Stress-inducible Gene (ZmRXO1) in Maize. Plant Mol Biol Rep (2015) 33:200–208
  20. Xinhua Sun, Gang Yu, Jingtao Li, Pan Jia, Jichao Zhang, Chengguo Jia, Yanhua Zhang and Hongyu Pan. A Heavy Metal-Associated Protein (AcHMA1) from the Halophyte, Atriplex canescens (Pursh) Nutt., Confers Tolerance to Iron and Other Abiotic Stresses When Expressed in Saccharomyces cerevisiae. Int. J. Mol. Sci. (2014) 15, 14891-14906.
  21. Fengting Wang, Jinliang Liu, Jingtao Li, Shihong Zhang, Hongyu Pan. Functional analyses of the maize CKS2 gene promoter in response to abiotic stresses and hormones. Acta Physiol Plant (2014) 36:1867–1878.
  22. 李明晨; 李跃; 李敬涛; 梁文星; 刘思慧。一种用于 PCR的丝状真菌 DNA快速粗提方法。青岛农业大学学报(自然科学版), 2022, 39(2): 122-127
  23. 申恒; 刘思慧; 李跃; 李敬涛; 梁文星。一种用于PCR的番茄DNA快速粗提方法。生物技术通报, 2022, 38(6): 74-80
  24. 李敬涛,余刚,陈宣明,范臻,刘金亮,潘洪玉 四翅滨藜AcDHN基因的克隆及其抗逆功能分析 植物生理学报 2012,48(7),676-682.
  25. 李敬涛,孙新华,余刚,贾承国,杜茜,李启云,潘洪玉 几种基于pCAMBIA系列多用途新型植物表达载体的改建及优化 《吉林大学学报(理学版)》 2014,52(2),371-375.
  26. 孙新华,李敬涛,刘言志,贾承国,潘洪玉 四翅滨藜AcERF1基因的克隆及其在酵母中的抗逆分析 植物生理学报 2013, 49 (8): 811~816
  27. 余刚,李敬涛,孙新华,刘金亮,潘洪玉 四翅滨藜LRR类受体蛋白激酶基因在酵母中的表达及其抗逆分析 《吉林大学学报(理学版)》 2012,50(6),1257-1263.

l 专利

  1. 李敬涛;杨莉梅;张香梅;王晨阳;钱永盼;宋丽敏;王光远。高良姜素在制备用于防治植物枯萎病的杀菌剂中的应用,2022-12-05,中国,CN 115812718 A
  2. 李敬涛;王晨阳; 李跃郑亚宁;梁文星; 王光远,李明晨。Rapid identification method of tomato fusarium wilt based on PCR2022.2.23,南非,2021/09761
  3. 李敬涛; 李跃; 王晨阳; 梁文星; 王光远 ; 一种基于PCR的番茄枯萎病的快速鉴定方法, 2021-11-19,中国, CN202111398877.7
  4. 梁文星; 徐敏; 王光远; 杨震宙; 李德龙; 李敬涛 ; 一株具有抑菌作用的拜赖青霉MP6及其应用, 2022-2-8, 中国, ZL202110663883.4
  5. 王光远; 刘子瑜; 张晓峰; 梁文星; 李德龙; 李敬涛 ; 一株具有抑菌作用的葡萄汁有孢汉逊酵母MP1861及其应用, 2022-2-1, 中国, ZL202110663876.4
  6. 四翅滨藜锌指蛋白基因克隆及其应用(潘洪玉;余刚;李敬涛;孙新华; 张祥辉;贾承国;刘金亮)专利号:ZL201410497473.7
  7. 四翅滨藜半胱氨酸蛋白酶基因克隆及其应用(潘洪玉;余刚;李敬涛;孙新华;贾承国;刘金亮;张祥辉)公开号:ZL201410497324
  8. 一种植物抗逆蛋白AcNAD及其编码蛋白的应用(潘洪玉;余刚;张世宏;刘金亮;陈宣明;李敬涛;贾承国;李桂华)专利号:ZL201110401191.9

七、社会兼职

1. 中国植物病理学会青年委员会委员。

2.山东省科技特派员。

3.Frontiers in Microbiology 审稿编辑。

八、联系方式

通讯地址:山东省青岛市城阳区长城路700号,青岛农业大学植物医学学院

邮政编码:266109

联系电话:17860709187

E-mail: lijingtao@qau.edu.cn

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